Primigyn (Dinoprostone) Gel 0.5% is a naturally-occurring Prostaglandin E2 (PGE2). In pregnancy, PGE2 is secreted continuously by the fetal membranes and placenta and plays an important role in the final events leading to the initiation of labor. It is known that PGE2 stimulates the production of PGF2 which in turn sensitizes the myometrium to endogenous or exogenously administrated oxytocin, this stimulation of the myometrium of the gravid uterus causes it to contract in a manner similar to contractions seen in the term uterus during labor.
For ripening and dilatation of an unfavorable cervix for labour induction.
Dosage & Administration
Please refer pack insert for further details
Syringe with a catheter for endocervical application